Search results for "nonspecific bronchial hyperresponsiveness"

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Bronchial hyperresponsiveness in children with atopic rhinitis: a 7-year follow-up

2004

Background:  A high prevalence of bronchial hyperresponsiveness (BHR) was found in atopic subjects with rhinitis. Those subjects may be at higher risk for developing bronchial asthma. We evaluated, in a 7-year follow-up, BHR and atopy in a homogeneous population of nonasthmatic children with allergic rhinitis (AR), and their role in asthma development. Methods:  Twenty-eight children (6–15 years) with AR were studied. At enrollment (T0), skin tests, total serum IgE assay, peak expiratory flow (PEF) monitoring and methacholine (Mch) bronchial challenge were performed. BHR was computed as the Mch dose causing a 20% forced expiratory volume (FEV)1 fall (PD20FEV1) and as dose–response slope (DR…

MaleAllergymedicine.medical_specialtyAdolescentAtopic RhinitisImmunologyPopulationLongitudinal StudieFollow-Up StudieAtopychildrennonspecific bronchial hyperresponsivenessInternal medicinemedicineHypersensitivityHumansImmunology and AllergyLongitudinal StudiesHumans; Disease Progression; Asthma; Child; Rhinitis; Longitudinal Studies; Hypersensitivity; Pulmonary Ventilation; Bronchial Hyperreactivity; Follow-Up Studies; Adolescent; Female; MaleeducationChildRhinitiRhinitisAsthmaeducation.field_of_studyallergic rhinitis; asthma; children; methacholine test; nonspecific bronchial hyperresponsivenessallergic rhinitisbusiness.industryRespiratory diseasemethacholine testrespiratory systemasthmamedicine.diseaserespiratory tract diseasesBronchial hyperresponsivenessImmunologyDisease ProgressionMethacholineFemaleBronchial HyperreactivitybusinessPulmonary VentilationFollow-Up Studiesmedicine.drugHuman
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